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1

Pyrrolomycins as potential anti-staphylococcal biofilms agents

Schillaci, Domenico, Petruso, Salvatore, Raimondi, Maria Valeria, Cusimano, Maria Grazia, Cascioferro, Stella, Scalisi, Marianna, La Giglia, Maria Anna, Vitale, Maria

Journal:

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

2

pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

Boritsch, Eva C., Frigui, Wafa, Cascioferro, Alessandro, Malaga, Wladimir, Etienne, Gilles, Laval, Françoise, Pawlik, Alexandre, Le Chevalier, Fabien, Orgeur, Mickael, Ma, Laurence, Bouchier, Christia

Journal:

Nature Microbiology

Year:

2016

Language:

english

File:

PDF, 3.31 MB

english, 2016

3

Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy

Parrino, Barbara, Diana, Patrizia, Cirrincione, Girolamo, Cascioferro, Stella

Journal:

The Open Medicinal Chemistry Journal

Year:

2018

Language:

english

File:

PDF, 212 KB

english, 2018

4

TCR density in early iNKT cell precursors regulates agonist selection and subset differentiation in mice

Joseph, Claudine, Klibi, Jihene, Amable, Ludivine, Comba, Lorenzo, Cascioferro, Alessandro, Delord, Marc, Parietti, Veronique, Lenoir, Christelle, Latour, Sylvain, Lucas, Bruno, Viret, Christophe, Tou

Journal:

European Journal of Immunology

Year:

2019

Language:

english

File:

PDF, 2.70 MB

english, 2019

5

Therapeutic strategies to counteract antibiotic resistance in MRSA biofilmâassociated infections

Cascioferro, Stella, Carbone, Daniela, Parrino, Barbara, Pecoraro, Camilla, Giovannetti, Elisa, Cirrincione, Girolamo, DIANA, PATRIZIA

Journal:

Year:

2020

File:

PDF, 1.48 MB

2020

6

1,2,4âOxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3Î² Kinase

Carbone, Daniela, Parrino, Barbara, Cascioferro, Stella, Pecoraro, Camilla, Giovannetti, Elisa, Di Sarno, Veronica, Musella, Simona, Auriemma, Giulia, Cirrincione, Girolamo, Diana, Patrizia

Journal:

Year:

2020

File:

PDF, 3.83 MB

2020

7

Pyrazolo[3,4-d]pyrimidine Derivatives as COX-2 Selective Inhibitors: Synthesis and Molecular Modelling Studies

Demetrio Raffa, Benedetta Maggio, Fabiana Plescia, Stella Cascioferro, Maria Valeria Raimondi, Salvatore Plescia, Maria Grazia Cusimano

Journal:

Archiv der Pharmazie

Year:

2009

Language:

english

File:

PDF, 3.59 MB

english, 2009

8

N-(Indazolyl)benzamido Derivatives as CDK1 Inhibitors: Design, Synthesis, Biological Activity, and Molecular Docking Studies

Demetrio Raffa, Benedetta Maggio, Stella Cascioferro, Maria Valeria Raimondi, Giuseppe Daidone, Salvatore Plescia, Domenico Schillaci, Maria Grazia Cusimano, Lucina Titone, Claudia Colomba, Manlio Tol

Journal:

Archiv der Pharmazie

Year:

2009

Language:

english

File:

PDF, 2.06 MB

english, 2009

9

Pyrazolobenzotriazinone Derivatives as COX Inhibitors: Synthesis, Biological Activity, and Molecular-Modeling Studies

Demetrio Raffa, Onofrio Migliara, Benedetta Maggio, Fabiana Plescia, Stella Cascioferro, Maria Grazia Cusimano, Giuseppe Tringali, Carla Cannizzaro, Fulvio Plescia

Journal:

Archiv der Pharmazie

Year:

2010

Language:

english

File:

PDF, 296 KB

english, 2010

10

Synthesis and Antileukemic Activity of New 3-(1-Phenyl-3-methylpyrazol-5-yl)-2-styrylquinazolin-4(3H)-ones.

Demetrio Raffa, Giuseppe Daidone, Benedetta Maggio, Stella Cascioferro, Fabiana Plescia, Domenico Schillaci

Journal:

Year:

2004

File:

PDF, 84 KB

2004

11

Synthesis and Antileukemic Activity of New 3-(5-Methylisoxazol-3-yl) and 3-(Pyrimidin-2-yl)-2-styrylquinazolin-4(3H)-ones.

Demetrio Raffa, Giuseppe Daidone, Benedetta Maggio, Stella Cascioferro, Fabiana Plescia, Domenico Schillaci

Journal:

Year:

2004

File:

PDF, 20 KB

2004

12

ChemInform Abstract: Pyrazolo[3,4-d]pyrimidine Derivatives as COX-2 Selective Inhibitors: Synthesis and Molecular Modelling Studies.

Demetrio Raffa, Benedetta Maggio, Fabiana Plescia, Stella Cascioferro, Maria Valeria Raimondi, Salvatore Plescia, Maria Grazia Cusimano

Journal:

Year:

2009

File:

PDF, 20 KB

2009

13

ChemInform Abstract: Pyrazolobenzotriazinone Derivatives as COX Inhibitors: Synthesis, Biological Activity, and Molecular-Modeling Studies.

Demetrio Raffa, Onofrio Migliara, Benedetta Maggio, Fabiana Plescia, Stella Cascioferro, Maria Grazia Cusimano, Giuseppe Tringali, Carla Cannizzaro, Fulvio Plescia

Journal:

Year:

2011

File:

PDF, 34 KB

2011

14

Synthesis and antimicrobial activity of new bromine-rich pyrrole derivatives related to monodeoxypyoluteorin

Maria Valeria Raimondi, Stella Cascioferro, Domenico Schillaci, Salvatore Petruso

Journal:

European Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 224 KB

english, 2006

15

Synthesis and induction of G0–G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-one

Benedetta Maggio, Demetrio Raffa, Maria Valeria Raimondi, Stella Cascioferro, Fabiana Plescia, Manlio Tolomeo, Eleonora Barbusca, Giuliana Cannizzo, Salvatrice Mancuso, Giuseppe Daidone

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 647 KB

english, 2008

16

Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides

Demetrio Raffa, Benedetta Maggio, Stella Cascioferro, Maria Valeria Raimondi, Domenico Schillaci, Giorgio Gallo, Giuseppe Daidone, Salvatore Plescia, Fiorella Meneghetti, Gabriella Bombieri, Antoniett

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 719 KB

english, 2009

17

Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides

Demetrio Raffa, Benedetta Maggio, Fabiana Plescia, Stella Cascioferro, Salvatore Plescia, Maria Valeria Raimondi, Giuseppe Daidone, Manlio Tolomeo, Stefania Grimaudo, Antonietta Di Cristina, Rosaria M

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

18

Synthesis of substituted 3-amino-N-phenyl-1H-indazole-1-carboxamides endowed with antiproliferative activity

Benedetta Maggio, Maria Valeria Raimondi, Demetrio Raffa, Fabiana Plescia, Stella Cascioferro, Salvatore Plescia, Manlio Tolomeo, Antonietta Di Cristina, Rosaria Maria Pipitone, Stefania Grimaudo, Giu

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 512 KB

english, 2011

19

PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall

Alessandro Cascioferro, Giovanni Delogu, Marisa Colone, Michela Sali, Annarita Stringaro, Giuseppe Arancia, Giovanni Fadda, Giorgio Palù, Riccardo Manganelli

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 448 KB

english, 2007

20

Synthesis and antileukemic activity of new 3-(1-phenyl-3-methylpyrazol-5-yl)-2-styrylquinazolin-4(3H)-ones

Demetrio Raffa, Giuseppe Daidone, Benedetta Maggio, Stella Cascioferro, Fabiana Plescia, Domenico Schillaci

Journal:

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

21

Synthesis and antileukemic activity of new 3-(5-methylisoxazol-3-yl) and 3-(pyrimidin-2-yl)-2-styrylquinazolin-4(3H)-ones

Demetrio Raffa, Giuseppe Daidone, Benedetta Maggio, Stella Cascioferro, Fabiana Plescia, Domenico Schillaci

Journal:

Year:

2004

Language:

english

File:

PDF, 182 KB

english, 2004

22

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis

Raffaella Iantomasi, Michela Sali, Alessandro Cascioferro, Ivana Palucci, Antonella Zumbo, Silvia Soldini, Stefano Rocca, Emanuela Greco, Giuseppe Maulucci, Marco De Spirito, Maurizio Fraziano, Giovan

Journal:

Cellular Microbiology

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

23

Synthesis and anti-staphylococcal activity of new 4-diazopyrazole derivatives

Raimondi, Maria Valeria, Maggio, Benedetta, Raffa, Demetrio, Plescia, Fabiana, Cascioferro, Stella, Cancemi, Gabriella, Schillaci, Domenico, Cusimano, Maria Grazia, Vitale, Maria, Daidone, Giuseppe

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 465 KB

english, 2012

24

In vitro anti-Gram-positive and antistaphylococcal biofilm activity of newly halogenated pyrroles related to pyrrolomycins

D. Schillaci, S. Petruso, S. Cascioferro, M.V. Raimondi, J.A.J. Haagensen, S. Molin

Journal:

International Journal of Antimicrobial Agents

Year:

2008

Language:

english

File:

PDF, 149 KB

english, 2008

25

Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3′,4′:2,3]azepino[4,5-f]azocine

Maggio, Benedetta, Raffa, Demetrio, Raimondi, Maria Valeria, Cusimano, Maria Grazia, Plescia, Fabiana, Cascioferro, Stella, Cancemi, Gabriella, Lauricella, Marianna, Carlisi, Daniela, Daidone, Giusepp

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 801 KB

english, 2014

26

Sortase A: An ideal target for anti-virulence drug development

Cascioferro, Stella, Totsika, Makrina, Schillaci, Domenico

Journal:

Microbial Pathogenesis

Year:

2014

Language:

english

File:

PDF, 384 KB

english, 2014

27

Analysis of SecA2-dependent substrates in M ycobacterium marinum identifies protein kinase G (PknG) as a virulence effector

van der Woude, Aniek D., Stoop, Esther J. M., Stiess, Michael, Wang, Sen, Ummels, Roy, van Stempvoort, Gunny, Piersma, Sander R., Cascioferro, Alessandro, Jiménez, Connie R., Houben, Edith N. G., Luir

Journal:

Cellular Microbiology

Year:

2014

Language:

english

File:

PDF, 776 KB

english, 2014

28

Antiadhesion agents against Gram-positive pathogens

Cascioferro, Stella, Cusimano, Maria Grazia, Schillaci, Domenico

Journal:

Future Microbiology

Year:

2014

Language:

english

File:

PDF, 1.72 MB

english, 2014

29

Mycobacterium tuberculosis evolutionary pathogenesis and its putative impact on drug development

Chevalier, Fabien Le, Cascioferro, Alessandro, Majlessi, Laleh, Herrmann, Jean Louis, Brosch, Roland

Journal:

Future Microbiology

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

30

Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle

Raffa, Demetrio, Maggio, Benedetta, Raimondi, Maria Valeria, Cascioferro, Stella, Plescia, Fabiana, Cancemi, Gabriella, Daidone, Giuseppe

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

31

4-Diazopyrazole Derivatives as Potential New Antibiofilm Agents

Schillaci, Domenico, Maggio, Benedetta, Raffa, Demetrio, Daidone, Giuseppe, Cascioferro, Stella, Cusimano, Maria Grazia, Raimondi, Maria Valeria

Journal:

Year:

2008

Language:

english

File:

PDF, 153 KB

english, 2008

32

Surface Expression of MPT64 as a Fusion with the PE Domain of PE_PGRS33 Enhances Mycobacterium bovis BCG Protective Activity against Mycobacterium tuberculosis in Mice

Sali, M., Di Sante, G., Cascioferro, A., Zumbo, A., Nicolo, C., Dona, V., Rocca, S., Procoli, A., Morandi, M., Ria, F., Palu, G., Fadda, G., Manganelli, R., Delogu, G.

Journal:

Infection and Immunity

Year:

2010

Language:

english

File:

PDF, 2.05 MB

english, 2010

33

Synthesis and antiproliferative activity of 3-(2-chloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one

Maggio, Benedetta, Raimondi, Maria Valeria, Raffa, Demetrio, Plescia, Fabiana, Cascioferro, Stella, Cancemi, Gabriella, Tolomeo, Manlio, Grimaudo, Stefania, Daidone, Giuseppe

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 824 KB

english, 2015

34

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis

Zumbo, Antonella, Palucci, Ivana, Cascioferro, Alessandro, Sali, Michela, Ventura, Marcello, D'Alfonso, Pamela, Iantomasi, Raffaella, Di Sante, Gabriele, Ria, Francesco, Sanguinetti, Maurizio, Fadda,

Journal:

Pathogens and Disease

Year:

2013

Language:

english

File:

PDF, 2.09 MB

english, 2013

35

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway

Daleke, M. H., Cascioferro, A., de Punder, K., Ummels, R., Abdallah, A. M., van der Wel, N., Peters, P. J., Luirink, J., Manganelli, R., Bitter, W.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.62 MB

english, 2011

36

Xer Site-Specific Recombination, an Efficient Tool To Introduce Unmarked Deletions into Mycobacteria

Cascioferro, A., Boldrin, F., Serafini, A., Provvedi, R., Palu, G., Manganelli, R.

Journal:

Applied and Environmental Microbiology

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

37

Sortase A Inhibitors: Recent Advances and Future Perspectives

Cascioferro, Stella, Raffa, Demetrio, Maggio, Benedetta, Raimondi, Maria Valeria, Schillaci, Domenico, Daidone, Giuseppe

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 5.30 MB

english, 2015

38

Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality

Raffa, Demetrio, Maggio, Benedetta, Plescia, Fabiana, Cascioferro, Stella, Raimondi, Maria Valeria, Cancemi, Gabriella, D’Anneo, Antonella, Lauricella, Marianna, Cusimano, Maria Grazia, Bai, Ruoli, Ha

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

39

A new class of phenylhydrazinylidene derivatives as inhibitors ofStaphylococcus aureusbiofilm formation

Cascioferro, Stella, Maggio, Benedetta, Raffa, Demetrio, Raimondi, Maria Valeria, Cusimano, Maria Grazia, Schillaci, Domenico, Manachini, Barbara, Leonchiks, Ainars, Daidone, Giuseppe

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 591 KB

english, 2016

40

Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta

Montalbano, Alessandra, Tesoriere, Luisa, Diana, Patrizia, Barraja, Paola, Carbone, Anna, Spanò, Virginia, Parrino, Barbara, Attanzio, Alessandro, Livrea, Maria Antonia, Cascioferro, Stella, Cirrincio

Journal:

Lebensmittel-Wissenschaft und-Technologie / Food Science and Technology

Year:

2016

Language:

english

File:

PDF, 364 KB

english, 2016

41

A peptide from human β thymosin as a platform for the development of new anti-biofilm agents forStaphylococcusspp. andPseudomonas aeruginosa

Schillaci, Domenico, Spinello, Angelo, Cusimano, Maria Grazia, Cascioferro, Stella, Barone, Giampaolo, Vitale, Maria, Arizza, Vincenzo

Journal:

World Journal of Microbiology and Biotechnology

Year:

2016

Language:

english

File:

PDF, 2.75 MB

english, 2016

42

ChemInform Abstract: Recent Advanced in Bioactive Systems Containing Pyrazole Fused with a Five Membered Heterocycle

Raffa, Demetrio, Maggio, Benedetta, Raimondi, Maria Valeria, Cascioferro, Stella, Plescia, Fabiana, Cancemi, Gabriella, Daidone, Giuseppe

Journal:

Year:

2015

File:

PDF, 12 KB

2015

43

Synthesis and biofilm formation reduction of pyrazole-4-carboxamide derivatives in some Staphylococcus aureus strains

Cascioferro, Stella, Maggio, Benedetta, Raffa, Demetrio, Raimondi, Maria Valeria, Cusimano, Maria Grazia, Schillaci, Domenico, Manachini, Barbara, Plescia, Fabiana, Daidone, Giuseppe

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

44

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis

Le Chevalier, Fabien, Cascioferro, Alessandro, Frigui, Wafa, Pawlik, Alexandre, Boritsch, Eva C., Bottai, Daria, Majlessi, Laleh, Herrmann, Jean Louis, Brosch, Roland

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

45

Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms

Schillaci, Domenico, Spanò, Virginia, Parrino, Barbara, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Diana, Patrizia, Cirrincione, Girolamo, Cascioferro, Stella Maria

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

46

Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives

Cascioferro, Stella, Parrino, Barbara, Spanò, Virginia, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Diana, Patrizia, Cirrincione, Girolamo

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

47

Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues

Parrino, Barbara, Attanzio, Alessandro, Spanò, Virginia, Cascioferro, Stella, Montalbano, Alessandra, Barraja, Paola, Tesoriere, Luisa, Diana, Patrizia, Cirrincione, Girolamo, Carbone, Anna

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

48

An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds

Cascioferro, Stella, Parrino, Barbara, Spanò, Virginia, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Diana, Patrizia, Cirrincione, Girolamo

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

49

Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis

Buchieri, Maria V., Cimino, Mena, Rebollo-Ramirez, Sonia, Beauvineau, Claire, Cascioferro, Alessandro, Favre-Rochex, Sandrine, Helynck, Olivier, Naud-Martin, Delphine, Larrouy-Maumus, Gerald, Munier-L

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

50

An overview of recent Molecular Dynamics applications as medicinal chemistry tool for undruggable sites challenge.

Perricone, Ugo, Gulotta, Maria Rita, Lombino, Jessica, Parrino, Barbara, Cascioferro, Stella, Diana, Patrizia, Cirrincione, Girolamo, Padova, Alessandro

Journal:

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018